points by giantg2 1 day ago

"This approach was also able to identify subgroups of children with different levels of cognitive control and performance monitoring, or the ability to modify one’s strategy after making an error."

This should surprise no one. You took a large population and found subpopulations within it. If you want to look at a population average, then use the population data. If you want to look at kids with specific attention needs (guessing ADHD since medical related) then design a study to select for children fitting that criteria, including subtypes.

This seems like the type of thing that should have had a study about study design done long ago that they could have followed to help them structure their own population selection.

salynchnew 20 hours ago

Often reminded of this passage from Hitchhiker's:

The Maximegalon Institute of Slowly and Painfully Working Out the Surprisingly Obvious (MISPWOSO) is a fictional research institution from Douglas Adams' The Hitchhiker's Guide to the Galaxy series.

bbor 21 hours ago

The point isn’t that they found subgroups, the point is the method they used to find them — namely, analyzing individual brain scans rather than averaging them out first.

  • giantg2 16 hours ago

    Same sort of thing - how would you expect to find subgroups by assigning the aggregate to individuals. It would be bad design. It's like they're surprised that they used a good design.

bongripper 23 hours ago

[flagged]

  • Eddy_Viscosity2 21 hours ago

    Medical professionals have a history of not necessarily having complete understanding of the maths they use in their work. Classic example of a nutritionist 'inventing' the trapezoid rule for calculating area under a curve, and then naming it after herself. And then many many other medical people unironically using said method and citing her.

    https://en.wikipedia.org/wiki/Tai%27s_model

    • bbor 21 hours ago

      A) these aren’t “medical people”, they’re neuroscientists and psychologists. Comparing them to a nutritionist seems especially cruel!

      B) “some people have been wrong before” is not a reason to think you know better than the authors of an upcoming Nature article based on a few layperson-targeted paragraphs summarizing the paper from a very high level.

      • JadeNB 21 hours ago

        > “some people have been wrong before” is not a reason to think you know better than the authors of an upcoming Nature article based on a few layperson-targeted paragraphs summarizing the paper from a very high level.

        Nor is "this paper is going to appear in Nature" a reason not to wonder whether there might be something that the authors don't know. The whole point of science is that anyone can make an informed critique and self-evaluation of it, with no necessity of depending on a priesthood to interpret it. You can point out the flaws in giantg2's argument https://news.ycombinator.com/item?id=47995899, but neither the venue of the paper, nor the fact that the argument is directed at laypeople in a forum frequented by laypeople, seems to me inherently to indicate such flaws.

        • mmooss 16 hours ago

          > The whole point of science is that anyone can make an informed critique and self-evaluation of it, with no necessity of depending on a priesthood to interpret it.

          That's a misinterpretation:

          > anyone can

          (Of course nothing stops them, but I don't think that's your point.)

          > anyone can make an informed critique and self-evaluation of it, with no necessity of depending on a priesthood to interpret it.

          Science is specifically not the wisdom of the crowds - that is pre-scientific. It is the wisdom of emprical facts, which are usually so complex and voluminous that it takes great expertise to understand and interpret them. Science is not democratic - your opinion is worthless and does not deserve consideration unless you can demonstrate otherwise.

          You don't have to be in the priesthood, but it's tough to have the expertise otherwise, and then tough to stay outside the priesthood.

          "'In matters of science,' Galileo wrote, 'the authority of thousands is not worth the humble reasoning of one single person.'" ("In questioni di scienza L'autorità di mille non vale l'umile ragionare di un singolo." The source was not able to verfy its provenance, however.)

          HN is democratic, however.

      • zipy124 17 hours ago

        Nature communications, not Nature. There is quite the large difference between them (and neither is neccessarily a sign of quality, but good ability to market well to an editor).

        For the record I have published in Nature Communications (and not Nature) and therefore know a little bit about what it takes to publish papers there.

    • mmooss 16 hours ago

      > Medical professionals have a history of not necessarily having complete understanding of the maths

      HN commenters have a far greater history of that.

      Also, researchers trained for years and invested a long time on this work; the HN commenter probably invested a minuted or two.

      • Eddy_Viscosity2 12 hours ago

        > HN commenters have a far greater history of that.

        It may very well be true, it is also true that HN commenters can be quite good at spotting math errors. The broader point being that people make mistakes sometimes or even that people sometimes don't have the same knowledge and information as others.

        > researchers trained for years and invested a long time on this work; the HN commenter probably invested a minuted or two

        Or it can also be postulated that the researchers were highly focused on the aspect of the work they were trained and interested in and may have lacked focus on the auxiliary fields. And that the HN commenter, while only spending a few minutes on this, was knowledgeable about the auxiliary field and immediately spotted a potential issue.

        This is actually great and why its good to get papers published and read by a wide audience, because nobody can be good at everything.

        • mmooss 11 hours ago

          > it is also true that HN commenters can be quite good at spotting math errors

          They can be quite good at making that claim, which is cheap. And others like to rally around it - just like the comments rejecting most OPs that make their way to the top.

          I'd need to see evidence that the claims are actually valid. Most similar HN take-downs, for fields I have knowledge of, are pretty poor.

          • Eddy_Viscosity2 59 minutes ago

            > I'd need to see evidence that the claims are actually valid.

            This would indeed be best, no argument here. But this comment thread was more about whether, without evidence, that automatically dismissing a comment because it was on HN or automatically accepting a claim because it was from 'stanford researchers' was ok.

  • JadeNB 21 hours ago

    That seems awfully like an appeal to authority. Your parent comment doesn't just vaguely snipe, but points out reasons this should have been expected. Those reasons could potentially not be valid, or not present the whole picture, but "the researchers are from Stanford" doesn't rebut them.

  • kelipso 17 hours ago

    A lot of people posting here are researchers too, and some have reviewed and published Nature articles too.